Date of Award
2018
Type
Thesis
Major
Chemistry
Degree Type
Bachelor of Arts
Department
Chemistry
First Advisor
Jonathan Meyers
Second Advisor
Kerri Taylor
Third Advisor
Cindy Ticknor
Abstract
There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.
Recommended Citation
Cardenas, Camila, "Antibiotic Effects of Dimethyl Sulfoxide and Synthetic Polyphenols on E. Coli Cells" (2018). Theses and Dissertations. 337.
https://csuepress.columbusstate.edu/theses_dissertations/337
