Date of Award

2018

Type

Thesis

Major

Art

Degree Type

Bachelor of Arts

Department

Chemistry

First Advisor

Jonathan Meyers

Second Advisor

Kerri Taylor

Third Advisor

Cindy Ticknor

Abstract

There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.

Included in

Chemistry Commons

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