Title

Synthesis and Anti-proliferative Activity of N,N′-bis-substituted 1,2,4-Triazolium Salts against Breast Cancer and Prostate Cancer Cell Lines

Document Type

Article

Publication Date

2-1-2019

Publication Title

Journal of Heterocyclic Chemistry

Volume

56

First Page

533

Last Page

538

Abstract

© 2018 Wiley Periodicals, Inc. A series of 1,4-N,N′-bis-substituted 1,2,4-triazolium bromide salts were synthesized and tested for anti-proliferative activity. 1,4-Bis(naphthalen-2-ylmethyl)-1,2,4-triazolium bromide (2) showed activity against MDA-MB-468 breast cancer and PC-3 prostate cancer cell lines.

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