Date of Award
2014
Type
Thesis
Major
Nursing
Degree Type
Bachelors of Science in Nursing
Department
School of Nursing
First Advisor
Lisa O'Steen
Second Advisor
Stacey Meyers-Prosyniuk
Third Advisor
Dr. Cindy Ticknor
Abstract
Preventing and Treating Complications of Sickle Cell Disease in Pediatric Patients Sickle cell anemia, also known as sickle cell disease, affects over 90,000 people in the United States alone with those of African descent being at greater risk (Dobson & Byrne, 2014). Worldwide, it affects over 30 million people (Khoury, Musallam, Mroueh, & Abboud, 2011). It is usually detected during first year of life. After that, it is a lifelong disease (Hollins et al., 2012). Patients with sickle cell disease in the United States are expected to live until they are approximately 48 years old (BMJ Group, 2011). It is classified as an autosomal recessive disorder ofthe blood. A child inherits abnormal hemoglobin from both their mother and father which causes their red blood cells to become distorted or sickled (Shiel, 2014). The hemoglobin that is abnormal is known as hemoglobin S or Hb S. Although the terms sickle cell anemia and sickle cell disease are often used interchangeably, sickle cell anemia is actually the most common type of sickle cell disease. Sickle cell anemia is the most common type of sickle disease and is caused by the homozygous state or Hb SS (Musumadi, Westerdale, & Appleby, 2012). Hb SS makes the red blood cell more "susceptible to be modulated by stress, hypoxia, and by the inflammatory response" (Odievre, Verger, Silva-Pinfo, & Elion, 2011, p. 533).
Recommended Citation
Ferguson, Keandra S., "Preventing and Treating Complications of Sickle Cell Disease in Pediatric Patients" (2014). Theses and Dissertations. 175.
https://csuepress.columbusstate.edu/theses_dissertations/175
